HABP2 Antibody
| Code | Size | Price |
|---|
| PSI-62-002-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Hyaluronan-binding protein 2, 3421-, Factor VII-activating protease, Factor seven-activating protease, FSAP, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding protein, Hyaluronan-binding protein 2 50 kDa heavy chain, Hyaluronan-binding protein 2 50 kDa heavy chain alternate form, Hyaluronan-binding protein 2 27 kDa light chain, Hyaluronan-binding protein 2 27 kDa light chain alternate form, HABP2, HGFAL, PHBP
Application Note:
For WB starting dilution is: 1:1000-1:2000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
HABP2 is an extracellular
serine protease that binds hyaluronic acid and is involved in cell
adhesion. The encoded protein is synthesized as a single chain, but
then undergoes an autoproteolytic event to form the functional
heterodimer. Further autoproteolysis leads to smaller, inactive
peptides. This protease is known to cleave urinary plasminogen
activator, coagulation factor VII, and the alpha and beta chains of
fibrinogen, but not prothrombin, plasminogen, or the gamma chain of
fibrinogen. Two transcript variants encoding different isoforms
have been found for this gene.
Background References:
- Choi-Miura, N.H., et al. Biol. Pharm. Bull. 24(2):140-143(2001)
- Sumiya, J., et al. J. Biochem. 122(5):983-990(1997)
- Choi-Miura, N.H., et al. J. Biochem. 119(6):1157-1165(1996)
- Gupta, S., et al. Eur. J. Cell Biol. 56(1):58-67(1991)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-408 amino acids from the C-terminal region of human HABP2.
NCBI Gene ID #:
3026
NCBI Official Name:
Hyaluronan-binding protein 2
NCBI Official Symbol:
HABP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q14520
Protein GI Number:
73919921
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14520
User NOte:
Optimal dilutions for each application to be determined by the researcher.