POLR2J Antibody
Code | Size | Price |
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PSI-55-770-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
DNA-directed RNA polymerase II subunit RPB11-a, RNA polymerase II subunit B11-a, RPB11a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 133 kDa subunit, POLR2J, POLR2J1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes a subunit of RNA polymerase II, the
polymerase responsible for synthesizing messenger RNA in
eukaryotes. The product of this gene exists as a heterodimer with
another polymerase subunit; together they form a core subassembly
unit of the polymerase. Two similar genes are located nearby on
chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
Background References:
- Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
- Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
- Shpakovskii, D.G., et al. Bioorg. Khim. 30(6):621-625(2004)
- Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100(22):12666-12671(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This POLR2J antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the C-terminal region of human POLR2J.
NCBI Gene ID #:
5439
NCBI Official Name:
DNA-directed RNA polymerase II subunit RPB11-a
NCBI Official Symbol:
POLR2J
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
P52435
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P52435
User NOte:
Optimal dilutions for each application to be determined by the researcher.