EIF2B4 Antibody
| Code | Size | Price |
|---|
| PSI-55-715-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta, EIF2B4, EIF2BD
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
Eukaryotic initiation factor 2B (EIF2B), which is
necessary for protein synthesis, is a GTP exchange factor composed
of five different subunits. The protein encoded by this gene is the
fourth, or delta, subunit. Defects in this gene are a cause of
leukoencephalopathy with vanishing white matter (VWM) and
ovarioleukodystrophy. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :
- Wu, Y., et al. J. Hum. Genet. 54(2):74-77(2009)
- Horzinski, L., et al. PLoS ONE(12), E8318 (2009) :
- Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This EIF2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4.
NCBI Gene ID #:
8890
NCBI Official Name:
Translation initiation factor eIF-2B subunit delta
NCBI Official Symbol:
EIF2B4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q9UI10
Protein GI Number:
28381357
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9UI10
User NOte:
Optimal dilutions for each application to be determined by the researcher.