MAF1 Antibody
| Code | Size | Price |
|---|
| PSI-55-086-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Repressor of RNA polymerase III transcription MAF1 homolog, MAF1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a protein that is similar to Maf1, a
Saccharomyces cerevisiae protein highly conserved in eukaryotic
cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol
III). It responds to changes in the cellular environment and
represses pol III transcription. Biochemical studies identified the
initiation factor TFIIIB as a target for Maf1-dependent repression.
Background References:
- Kantidakis, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11823-11828(2010)
- Shor, B., et al. J. Biol. Chem. 285(20):15380-15392(2010)
- Johnson, S.S., et al. Mol. Cell 26(3):367-379(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This MAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human MAF1.
NCBI Gene ID #:
84232
NCBI Official Name:
Repressor of RNA polymerase III transcription MAF1 homolog
NCBI Official Symbol:
MAF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
Q9H063
Protein GI Number:
296434582
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H063
User NOte:
Optimal dilutions for each application to be determined by the researcher.