IGFBP3 Antibody

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ProSci
Product Code: PSI-63-091
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-63-091-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Saccharomyces cerevisiae
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in CHO tissue lysates (15ug/lane).This demonstrates the IGFBP antibody detected IGFBP protein (arrow).
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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in CHO tissue lysates (15ug/lane).This demonstrates the IGFBP antibody detected IGFBP protein (arrow).

Documents

Further Information

Additional Names:
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, IGFBP3, IBP3
Application Note:
For WB starting dilution is: 1:1000
Background:
IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Background References:
  • Muzumdar,R.H., Diabetes 55 (10), 2788-2796 (2006) Novosyadlyy,R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Immunogen:
This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from human IGFBP3.
NCBI Gene ID #:
3486
NCBI Official Name:
Insulin-like growth factor-binding protein 3
NCBI Official Symbol:
IGFBP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P17936
Protein GI Number:
146327827
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P17936
User NOte:
Optimal dilutions for each application to be determined by the researcher.