PTGES3 Antibody

ProSci
Product Code: PSI-57-961
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-961-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: A549 whole cell lysate Lane 4: mouse testis lysate Lane 5: rat testis lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: A549 whole cell lysate Lane 4: mouse testis lysate Lane 5: rat testis lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23, PTGES3, P23, TEBP
Application Note:
For WB starting dilution is: 1:2000
Background:
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Background References:
  • Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7401-7406(2010)
  • Lee, J.H., et al. Cancer Lett. 290(1):76-86(2010)
  • Chadli, A., et al. J. Biol. Chem. 285(6):4224-4231(2010)
  • Woo, S.H., et al. J. Biol. Chem. 284(45):30871-30880(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Bovine
Immunogen:
This PTGES3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human PTGES3.
NCBI Gene ID #:
10728
NCBI Official Name:
Prostaglandin E synthase 3
NCBI Official Symbol:
PTGES3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
Q15185
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Immunology,Obesity,Signal Transduction
Swissprot #:
Q15185
User NOte:
Optimal dilutions for each application to be determined by the researcher.