WNT5A Antibody
| Code | Size | Price |
|---|
| PSI-62-006-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein Wnt-5a, WNT5A
Application Note:
For WB starting dilution is: 1:500
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
The WNT gene family consists of structurally related genes
which encode secreted signaling proteins. These proteins have been
implicated in oncogenesis and in several developmental processes,
including regulation of cell fate and patterning during
embryogenesis. This gene is a member of the WNT gene family. It
encodes a protein which shows 98%, 98% and 87% amino acid identity
to the mouse, rat and the xenopus Wnt5A protein, respectively. The
experiments performed in Xenopus laevis embryos identified that
human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and
the Wnt5A/hFz5 signaling mediates axis induction. [provided by
RefSeq].
Background References:
- He, X., et al. Science 275(5306):1652-1654(1997)
- Danielson, K.G., et al. J. Biol. Chem. 270(52):31225-31234(1995)
- Smolich, B.D., et al. Mol. Biol. Cell 4(12):1267-1275(1993)
- Clark, C.C., et al. Genomics 18(2):249-260(1993)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rabbit
Immunogen:
This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human WNT5A.
NCBI Gene ID #:
7474
NCBI Official Name:
Protein Wnt-5a
NCBI Official Symbol:
WNT5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P41221
Protein GI Number:
212276478
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P41221
User NOte:
Optimal dilutions for each application to be determined by the researcher.