YY1 Antibody
Code | Size | Price |
---|
PSI-61-408-400ul | 400ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1, INO80S
Application Note:
For WB starting dilution is: 1:1000
Background:
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Background References:
- Sucharov, C.C., et al., J. Biol. Chem. 278(33):31233-31239 (2003). Kurisaki, K., et al., Mol. Cell. Biol. 23(13):4494-4510 (2003). Huang, N.E., et al., Biochem. Biophys. Res. Commun. 306(1):267-275 (2003). Moriuchi, M., et al., J. Biol. Chem. 278(15):13003-13007 (2003). Hiromura, M., et al., J. Biol. Chem. 278(16):14046-14052 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This YY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human YY1.
NCBI Gene ID #:
7528
NCBI Official Name:
Transcriptional repressor protein YY1
NCBI Official Symbol:
YY1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P25490
Protein GI Number:
3915889
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Load Control Antibodies
Swissprot #:
P25490
User NOte:
Optimal dilutions for each application to be determined by the researcher.