GDI1 Antibody
| Code | Size | Price |
|---|
| PSI-60-860-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDI1, GDIL, OPHN2, RABGDIA, XAP4
Application Note:
For WB starting dilution is: 1:1000-1:2000
Background:
GDP dissociation inhibitors are proteins that regulate the
GDP-GTP exchange reaction of members of the rab family, small
GTP-binding proteins of the ras superfamily, that are involved in
vesicular trafficking of molecules between cellular organelles.
GDIs slow the rate of dissociation of GDP from rab proteins and
release GDP from membrane-bound rabs. GDI1 is expressed primarily
in neural and sensory tissues. Mutations in GDI1 have been linked
to X-linked nonspecific mental retardation.
Background References:
- Martins-de-Souza, D., et al.Psychiatr Res 44(14):989-991(2010)
- Massignan, T., et al. Mol. Cell Proteomics 9(4):611-622(2010)
- Chen, Y., et al. Biochem. J. 422(2):229-235(2009)
- Zhang, K.J., et al. Yi Chuan 30(5):590-594(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.
NCBI Gene ID #:
2664
NCBI Official Name:
Rab GDP dissociation inhibitor alpha
NCBI Official Symbol:
GDI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P31150
Protein GI Number:
1707886
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P31150
User NOte:
Optimal dilutions for each application to be determined by the researcher.