VAMP3 Antibody
Code | Size | Price |
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PSI-57-894-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Zebrafish
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD
synaptosomal-associated protein are the main components of a
protein complex involved in the docking and/or fusion of synaptic
vesicles with the presynaptic membrane. This gene is a member of
the vesicle-associated membrane protein (VAMP)/synaptobrevin
family. Because of its high homology to other known VAMPs, its
broad tissue distribution, and its subcellular localization, the
protein encoded by this gene was shown to be the human equivalent
of the rodent cellubrevin. In platelets the protein resides on a
compartment that is not mobilized to the plasma membrane on calcium
or thrombin stimulation.
Background References:
- Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
- Fader, C.M., et al. Biochim. Biophys. Acta 1793(12):1901-1916(2009)
- Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
- Vassilopoulos, S., et al. Science 324(5931):1192-1196(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat, Monkey
Immunogen:
This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3.
NCBI Gene ID #:
9341
NCBI Official Name:
Vesicle-associated membrane protein 3
NCBI Official Symbol:
VAMP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
11 kDa
Protein Accession #:
Q15836
Protein GI Number:
2501082
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction,
Swissprot #:
Q15836
User NOte:
Optimal dilutions for each application to be determined by the researcher.