RAC1 Antibody

ProSci
Product Code: PSI-63-008
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-008-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 3
Western Blot at 1:2000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: rat brain lysate Lysates/proteins at 20 ug per lane.
2 / 3
Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.
3 / 3

Western Blot at 1:2000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: rat brain lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1, RAC1, TC25
Application Note:
For WB starting dilution is: 1:2000
Background:
RAC1 is a GTPase belonging to the RAS superfamily of small GTP-binding proteins. It is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells).
Background References:
  • Wang,T.,Neurosci. Lett. 437 (2), 71-75 (2008)
  • Gorshkova,I., J. Biol. Chem. 283 (17), 11794-11806 (2008)
  • Simeone-Penney,M.C.,Am. J. Physiol. Lung Cell Mol. Physiol. 294 (4), L698-L704 (2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, C. Elegans, Chicken, Drosophila, Monkey, Mouse, Pig
Immunogen:
This RAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human RAC1.
NCBI Gene ID #:
5879
NCBI Official Name:
Ras-related C3 botulinum toxin substrate 1
NCBI Official Symbol:
RAC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P63000
Protein GI Number:
51702787
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction,
Swissprot #:
P63000
User NOte:
Optimal dilutions for each application to be determined by the researcher.