RAB11B Antibody

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ProSci
Product Code: PSI-56-750
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-750-400ul400ul£662.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: rat brain lysates Lane 2: rat testis lysates Lane 3: human brain lysates Lane 4: human testis lysates Lysates/proteins at 20 ug per lane.
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RAB11B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western Blot at 1:1000 dilution Lane 1: rat brain lysates Lane 2: rat testis lysates Lane 3: human brain lysates Lane 4: human testis lysates Lysates/proteins at 20 ug per lane.
RAB11B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM].
Background References:
  • Agop-Nersesian, C., et al. PLoS Pathog.(7), E1001029 (2010) :
  • Silvis, M.R., et al. Mol. Biol. Cell 20(8):2337-2350(2009)
  • Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)
  • Scapin, S.M., et al. J. Struct. Biol. 154(3):260-268(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This RAB11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human RAB11B.
NCBI Gene ID #:
9230
NCBI Official Name:
Ras-related protein Rab-11B
NCBI Official Symbol:
RAB11B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q15907
Protein GI Number:
38258938
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q15907
User NOte:
Optimal dilutions for each application to be determined by the researcher.