CNBP Antibody
| Code | Size | Price |
|---|
| PSI-60-967-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9
Application Note:
For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene encodes a nucleic-acid binding protein with
seven zinc-finger domains. The protein has a preference for binding
single stranded DNA and RNA. The protein functions in
cap-independent translation of ornithine decarboxylase mRNA, and
may also function in sterol-mediated transcriptional regulation. A
CCTG expansion in the first intron of this gene results in myotonic
dystrophy type 2. Multiple transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Catalli, C., et al.Mol Diagn 12(5):601-606(2010)
- Massa, R., et al. Neuropathol. Appl. Neurobiol. 36(4):275-284(2010)
- Sammons, M.A., et al. PLoS ONE(2), E9301 (2010) :
- Lucchiari, S., et al. J. Neurol. Sci. 275 (1-2), 159-163 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse
Immunogen:
This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.
NCBI Gene ID #:
7555
NCBI Official Name:
Cellular nucleic acid-binding protein
NCBI Official Symbol:
CNBP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
P62633
Protein GI Number:
50401852
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P62633
User NOte:
Optimal dilutions for each application to be determined by the researcher.