Mouse Dyrk1b Antibody
| Code | Size | Price |
|---|
| PSI-57-862-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Dyrk1b
Application Note:
For WB starting dilution is: 1:1000
Background:
Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.
Background References:
- Janumyan, Y., et al. J. Biol. Chem. 283(49):34108-34120(2008)
- Munton, R.P., et al. Mol. Cell Proteomics 6(2):283-293(2007)
- Mercer, S.E., et al. J. Biol. Chem. 280(27):25788-25801(2005)
- Collins, M.O., et al. J. Biol. Chem. 280(7):5972-5982(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Mouse Dyrk1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-403 amino acids from the Central region of mouse Dyrk1b.
NCBI Gene ID #:
13549
NCBI Official Name:
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
NCBI Official Symbol:
Dyrk1b
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
Q9Z188
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9Z188
User NOte:
Optimal dilutions for each application to be determined by the researcher.