HOXB13 Antibody
Code | Size | Price |
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PSI-60-353-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Homeobox protein Hox-B13, HOXB13
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a transcription factor that belongs to
the homeobox gene family. Genes of this family are highly conserved
among vertebrates and essential for vertebrate embryonic
development. This gene has been implicated to play a role in fetal
skin development and cutaneous regeneration. In mice, a similar
gene was shown to exhibit temporal and spatial colinearity in the
main body axis of the embryo, but was not expressed in the
secondary axes, which suggests functions in body patterning along
the axis. This gene and other HOXB genes form a gene cluster at
chromosome the 17q21-22 region.
Background References:
- McMullin, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107(1):98-103(2010)
- Kim, Y.R., et al. Mol. Cancer 9, 124 (2010) :
- Norris, J.D., et al. Mol. Cell 36(3):405-416(2009)
- Goetz, M.P., et al. Clin. Cancer Res. 14(18):5864-5868(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish
Immunogen:
This HOXB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human HOXB13.
NCBI Gene ID #:
10481
NCBI Official Name:
Homeobox protein Hox-B13
NCBI Official Symbol:
HOXB13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
Q92826
Protein GI Number:
50403792
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q92826
User NOte:
Optimal dilutions for each application to be determined by the researcher.