LRIG1 Antibody

ProSci
Product Code: PSI-60-704
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-704-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse stomach tissue lysates (35ug/lane).

Western blot analysis in mouse stomach tissue lysates (35ug/lane).

Further Information

Additional Names:
Leucine-rich repeats and immunoglobulin-like domains protein 1, LIG-1, LRIG1, LIG1
Application Note:
For WB starting dilution is: 1:1000
Background:
LRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Ye, F., et al. J. Neurooncol. 94(2):183-194(2009)
  • Ljuslinder, I., et al. Breast Cancer Res. 11 (3), 403 (2009) :
  • Miller, J.K., et al. Cancer Res. 68(20):8286-8294(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LRIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 801-829 amino acids from the C-terminal region of human LRIG1.
NCBI Gene ID #:
26018
NCBI Official Name:
Leucine-rich repeats and immunoglobulin-like domains protein 1
NCBI Official Symbol:
LRIG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
119 kDa
Protein Accession #:
Q96JA1
Protein GI Number:
143811415
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q96JA1
User NOte:
Optimal dilutions for each application to be determined by the researcher.