Mouse Matk Antibody

ProSci
Product Code: PSI-57-608
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-608-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
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Mouse Matk Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Mouse Matk Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Megakaryocyte-associated tyrosine-protein kinase, Protein kinase NTK, Tyrosine-protein kinase CTK, Matk, Ctk, Ntk
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Background References:
  • Lee, B.C., et al. Blood 108(3):904-907(2006)
  • Robinson, D.R., et al. Oncogene 19(49):5548-5557(2000)
  • Puttagunta, R., et al. Genome Res. 10(9):1369-1380(2000)
  • Samokhvalov, I., et al. Biochem. Mol. Biol. Int. 43(1):115-122(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Matk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of mouse Matk.
NCBI Gene ID #:
17179
NCBI Official Name:
Megakaryocyte-associated tyrosine-protein kinase
NCBI Official Symbol:
Matk
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P41242
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P41242
User NOte:
Optimal dilutions for each application to be determined by the researcher.