PLXNC1 Antibody

ProSci
Product Code: PSI-57-132
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-132-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis in mouse liver tissue lysates (35ug/lane).
2 / 2
PLXNC1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in mouse liver tissue lysates (35ug/lane).
PLXNC1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Plexin-C1, Virus-encoded semaphorin protein receptor, CD232, PLXNC1, VESPR
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
PLXNC1 is a receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).
Background References:
  • Liu, H., et al. Cell 142(5):749-761(2010)
  • Lazova, R., et al. AmDermatopathol 31(2):177-181(2009)
  • Scott, G.A., et al. J. Invest. Dermatol. 129(4):954-963(2009)
  • Scott, G.A., et al. J. Invest. Dermatol. 128(1):151-161(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLXNC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from the C-terminal region of human PLXNC1.
NCBI Gene ID #:
10154
NCBI Official Name:
Plexin-C1
NCBI Official Symbol:
PLXNC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
176 kDa
Protein Accession #:
O60486
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
O60486
User NOte:
Optimal dilutions for each application to be determined by the researcher.