LTBR Antibody
| Code | Size | Price |
|---|
| PSI-58-208-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) family of receptors. It is expressed on the
surface of most cell types, including cells of epithelial and
myeloid lineages, but not on T and B lymphocytes. The protein
specifically binds the lymphotoxin membrane form (a complex of
lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its
ligand play a role in the development and organization of lymphoid
tissue and tranformed cells. Activation of the encoded protein can
trigger apoptosis.
Background References:
- Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
- Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
- Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LTBR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human LTBR.
NCBI Gene ID #:
4055
NCBI Official Name:
Tumor necrosis factor receptor superfamily member 3
NCBI Official Symbol:
LTBR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P36941
Protein GI Number:
549090
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction
Swissprot #:
P36941
User NOte:
Optimal dilutions for each application to be determined by the researcher.