PPP2CA Antibody
| Code | Size | Price |
|---|
| PSI-60-912-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the phosphatase 2A catalytic subunit.
Protein phosphatase 2A is one of the four major Ser/Thr
phosphatases, and it is implicated in the negative control of cell
growth and division. It consists of a common heteromeric core
enzyme, which is composed of a catalytic subunit and a constant
regulatory subunit, that associates with a variety of regulatory
subunits. This gene encodes an alpha isoform of the catalytic
subunit.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Jayadeva, G., et al. J. Biol. Chem. 285(39):29863-29873(2010)
- Pradhan, S., et al. J. Biol. Chem. 285(38):29059-29068(2010)
- Schmitz, M.H., et al. Nat. Cell Biol. 12(9):886-893(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Pig, Rabbit, Rat, Drosophila
Immunogen:
This PPP2CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human PPP2CA.
NCBI Gene ID #:
5515
NCBI Official Name:
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
NCBI Official Symbol:
PPP2CA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
P67775
Protein GI Number:
54038809
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
P67775
User NOte:
Optimal dilutions for each application to be determined by the researcher.