CYP5A1 Antibody
| Code | Size | Price |
|---|
| PSI-56-215-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Thromboxane-A synthase, TXA synthase, TXS, Cytochrome P450 5A1, TBXAS1, CYP5, CYP5A1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
However, this protein is considered a member of the cytochrome P450
superfamily on the basis of sequence similarity rather than
functional similarity. This endoplasmic reticulum membrane protein
catalyzes the conversion of prostglandin H2 to thromboxane A2, a
potent vasoconstrictor and inducer of platelet aggregation. The
enzyme plays a role in several pathophysiological processes
including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Wang, L.H., et al. Prostaglandins Other Lipid Mediat. 68-69, 409-422 (2002) :
- Tazawa, R., et al. Arch. Biochem. Biophys. 334(2):349-356(1996)
- Baek, S.J., et al. Gene 173(2):251-256(1996)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.
NCBI Gene ID #:
6916
NCBI Official Name:
Thromboxane-A synthase
NCBI Official Symbol:
TBXAS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P24557
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P24557
User NOte:
Optimal dilutions for each application to be determined by the researcher.