Mouse Insr Antibody
Code | Size | Price |
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PSI-57-867-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Insulin receptor, IR, CD220, Insulin receptor subunit alpha, Insulin receptor subunit beta, Insr
Application Note:
For WB starting dilution is: 1:1000
Background:
This receptor binds insulin and has a tyrosine-protein kinase activity. When present in a hybrid receptor with IGF1R, binds IGF1.
Background References:
- Brothers, K.J., et al. Cell Metab. 12(3):295-305(2010)
- Divall, S.A., et al. J. Clin. Invest. 120(8):2900-2909(2010)
- Fulzele, K., et al. Cell 142(2):309-319(2010)
- Ferron, M., et al. Cell 142(2):296-308(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Insr antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 546-574 amino acids from the Central region of mouse Insr.
NCBI Gene ID #:
16337
NCBI Official Name:
Insulin receptor
NCBI Official Symbol:
Insr
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
156 kDa
Protein Accession #:
P15208
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P15208
User NOte:
Optimal dilutions for each application to be determined by the researcher.