Mouse Fyn Antibody
| Code | Size | Price |
|---|
| PSI-58-032-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn, Fyn
Application Note:
For WB starting dilution is: 1:1000
Background:
Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Background References:
- Garcia-Roman, J., et al. Biochem. Biophys. Res. Commun. 401(2):262-267(2010)
- Cannons, J.L., et al. J. Immunol. 185(5):2819-2827(2010)
- Zheng, Y., et al. Mol. Cell. Biol. 30(17):4280-4292(2010)
- Ohnishi, H., et al. J. Neurosci. 30(31):10472-10483(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Human, Pig, Rat
Immunogen:
This Mouse Fyn antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-535 amino acids from the C-terminal region of mouse Fyn.
NCBI Gene ID #:
14360
NCBI Official Name:
Tyrosine-protein kinase Fyn
NCBI Official Symbol:
Fyn
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P39688
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P39688
User NOte:
Optimal dilutions for each application to be determined by the researcher.