Mouse Prkcd Antibody
Code | Size | Price |
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PSI-57-869-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, Prkcd, Pkcd
Application Note:
For WB starting dilution is: 1:1000
Background:
This is calcium-independent, phospholipid-dependent, serine-and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin (By similarity).
Background References:
- Ronda, A.C., et al. J. Steroid Biochem. Mol. Biol. 122(4):287-294(2010)
- Li, X., et al. J. Am. Soc. Nephrol. 21(7):1115-1124(2010)
- Romanova, L.Y., et al. J. Cell. Sci. 123 (PT 9), 1567-1577 (2010) :
- White, M.C., et al. PLoS Genet.(6), E1000984 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Prkcd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of mouse Prkcd.
NCBI Gene ID #:
18753
NCBI Official Name:
Protein kinase C delta type
NCBI Official Symbol:
Prkcd
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
78 kDa
Protein Accession #:
P28867
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
P28867
User NOte:
Optimal dilutions for each application to be determined by the researcher.