GLI1 Antibody

ProSci
Product Code: PSI-61-157
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-157-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1, GLI
Application Note:
For WB starting dilution is: 1:2000
Background:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
Background References:
  • Kinzler K.W.,et al.Nature 332:371-374(1988).
  • Yoon J.W.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
  • Lo H.W.,et al.Cancer Res. 69:6790-6798(2009).
  • Scherer S.E.,et al.Nature 440:346-351(2006).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GLI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-230 amino acids from human GLI1.
NCBI Gene ID #:
2735
NCBI Official Name:
Zinc finger protein GLI1
NCBI Official Symbol:
GLI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
118 kDa
Protein Accession #:
P08151
Protein GI Number:
121323
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Stem Cell
Swissprot #:
P08151
User NOte:
Optimal dilutions for each application to be determined by the researcher.