Mouse Sin3a Antibody
| Code | Size | Price |
|---|
| PSI-60-396-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a, Transcriptional corepressor Sin3a, Sin3a, Kiaa4126
Application Note:
For WB starting dilution is: 1:1000
Background:
Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
Background References:
- Baltus, G.A., et al. J. Biol. Chem. 284(11):6998-7006(2009)
- Anderson, D.M., et al. Dev. Dyn. 238(3):572-580(2009)
- Chang, S., et al. J. Immunol. 181(12):8372-8381(2008)
- van Oevelen, C., et al. Mol. Cell 32(3):359-370(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.
NCBI Gene ID #:
20466
NCBI Official Name:
Paired amphipathic helix protein Sin3a
NCBI Official Symbol:
Sin3a
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
145 kDa
Protein Accession #:
Q60520
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
Q60520
User NOte:
Optimal dilutions for each application to be determined by the researcher.