Mouse Acvr1c Antibody
| Code | Size | Price |
|---|
| PSI-57-853-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, Acvr1c {ECO:0000312|EMBL:AAH287801}
Application Note:
For WB starting dilution is: 1:1000
Background:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Background References:
- Andersson, O., et al. Proc. Natl. Acad. Sci. U.S.A. 105(20):7252-7256(2008)
- Bertolino, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105(20):7246-7251(2008)
- Liguori, G.L., et al. Dev. Biol. 315(2):280-289(2008)
- Kurrasch, D.M., et al. J. Neurosci. 27(50):13624-13634(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Human, Rat
Immunogen:
This Mouse Acvr1c antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-368 amino acids from the C-terminal region of mouse Acvr1c.
NCBI Gene ID #:
269275
NCBI Official Name:
Activin receptor type-1C
NCBI Official Symbol:
Acvr1c
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q8K348
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8K348
User NOte:
Optimal dilutions for each application to be determined by the researcher.