Mouse Erbb2 Antibody
| Code | Size | Price |
|---|
| PSI-58-126-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu
Application Note:
For WB starting dilution is: 1:1000
Background:
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).
Background References:
- Cabodi, S., et al. FASEB J. 24(10):3796-3808(2010)
- Johnson, E., et al. J. Biol. Chem. 285(38):29491-29501(2010)
- Huck, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15559-15564(2010)
- Chuang, T.D., et al. J. Biol. Chem. 285(31):23598-23606(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Erbb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of mouse Erbb2.
NCBI Gene ID #:
13866
NCBI Official Name:
Receptor tyrosine-protein kinase erbB-2
NCBI Official Symbol:
Erbb2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
139 kDa
Protein Accession #:
P70424
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P70424
User NOte:
Optimal dilutions for each application to be determined by the researcher.