LGALS3BP Antibody
| Code | Size | Price |
|---|
| PSI-60-709-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Tumor-associated antigen 90K, LGALS3BP, M2BP
Application Note:
For WB starting dilution is: 1:1000
Background:
The galectins are a family of beta-galactoside-binding
proteins implicated in modulating cell-cell and cell-matrix
interactions. LGALS3BP has been found elevated in the serum of
patients with cancer and in those infected by the human
immunodeficiency virus (HIV). It appears to be implicated in immune
response associated with natural killer (NK) and
lymphokine-activated killer (LAK) cell cytotoxicity. Using
fluorescence in situ hybridization the full length 90K cDNA has
been localized to chromosome 17q25. The native protein binds
specifically to a human macrophage-associated lectin known as Mac-2
and also binds galectin 1.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Srirajaskanthan, R., et al. Mol. Cell Proteomics 9(4):656-666(2010)
- Zambelli, D., et al. Int. J. Cancer 126(1):41-52(2010)
- Lee, J.H., et al. Pathology 41(3):229-233(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
NCBI Gene ID #:
3959
NCBI Official Name:
Galectin-3-binding protein
NCBI Official Symbol:
LGALS3BP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q08380
Protein GI Number:
47115668
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q08380
User NOte:
Optimal dilutions for each application to be determined by the researcher.