FGF20 Antibody

ProSci
Product Code: PSI-60-454
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-454-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in mouse kidney tissue lysates (35ug/lane).

Western blot analysis in mouse kidney tissue lysates (35ug/lane).

Further Information

Additional Names:
Fibroblast growth factor 20, FGF-20, FGF20
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
Background References:
  • de Mena, L., et al. Neurosci. Lett. 479(1):22-25(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Lemaitre, H., et al. J. Neurosci. 30(17):5992-5997(2010)
  • Maity, H., et al. Curr Pharm Biotechnol 10(6):609-625(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This FGF20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF20.
NCBI Gene ID #:
26281
NCBI Official Name:
Fibroblast growth factor 20
NCBI Official Symbol:
FGF20
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q9NP95
Protein GI Number:
13626702
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9NP95
User NOte:
Optimal dilutions for each application to be determined by the researcher.