Mouse Senp1 Antibody
| Code | Size | Price |
|---|
| PSI-60-665-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sentrin-specific protease 1, SUMO-1 protease 2, SuPr-2, Sentrin/SUMO-specific protease SENP1, Senp1, Supr2
Application Note:
For WB starting dilution is: 1:1000
Background:
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
Background References:
- Bawa-Khalfe, T., et al. J. Biol. Chem. 285(33):25859-25866(2010)
- Yu, L., et al. J. Exp. Med. 207(6):1183-1195(2010)
- Sharma, P., et al. J. Cell. Sci. 123 (PT 8), 1227-1234 (2010) :
- Li, X., et al. Cell Death Differ. 15(4):739-750(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Senp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-289 amino acids from the Central region of mouse Senp1.
NCBI Gene ID #:
223870
NCBI Official Name:
Sentrin-specific protease 1
NCBI Official Symbol:
Senp1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
P59110
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P59110
User NOte:
Optimal dilutions for each application to be determined by the researcher.