FBXO22 Antibody

ProSci
Product Code: PSI-60-086
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-086-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse heart tissue lysates (35ug/lane).

Western blot analysis in mouse heart tissue lysates (35ug/lane).

Further Information

Additional Names:
F-box only protein 22, F-box protein FBX22p44, FBXO22, FBX22
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.
Background References:
  • Borziak, K., et al. Bioinformatics 23(19):2518-2521(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
  • Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FBXO22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the C-terminal region of human FBXO22.
NCBI Gene ID #:
26263
NCBI Official Name:
F-box only protein 22
NCBI Official Symbol:
FBXO22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q8NEZ5
Protein GI Number:
30580428
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8NEZ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.