BRD7 Antibody

ProSci
Product Code: PSI-57-053
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-053-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in mouse heart tissue lysates (35ug/lane).

Western blot analysis in mouse heart tissue lysates (35ug/lane).

Further Information

Additional Names:
Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Background References:
  • Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14280-14285(2010)
  • Drost, J., et al. Nat. Cell Biol. 12(4):380-389(2010)
  • Kikuchi, M., et al. Biochim. Biophys. Acta 1793(12):1828-1836(2009)
  • Kaeser, M.D., et al. J. Biol. Chem. 283(47):32254-32263(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.
NCBI Gene ID #:
29117
NCBI Official Name:
Bromodomain-containing protein 7
NCBI Official Symbol:
BRD7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q9NPI1
Protein GI Number:
74734307
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9NPI1
User NOte:
Optimal dilutions for each application to be determined by the researcher.