FBXO8 Antibody
Code | Size | Price |
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PSI-60-087-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
F-box only protein 8, F-box/SEC7 protein FBS, FBXO8, FBS, FBX8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbxs class. It contains a C-terminal amino acid
sequence that bears a significant similarity with a portion of
yeast Sec7p, a critical regulator of vesicular protein transport.
This human protein may interact with ADP-ribosylation
factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange
factor) activity.
Background References:
- Cronin, S., et al. Eur. J. Hum. Genet. 17(2):213-218(2009)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
- Ilyin, G.P., et al. Genomics 67(1):40-47(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This FBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8.
NCBI Gene ID #:
26269
NCBI Official Name:
F-box only protein 8
NCBI Official Symbol:
FBXO8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q9NRD0
Protein GI Number:
13124142
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9NRD0
User NOte:
Optimal dilutions for each application to be determined by the researcher.