UBASH3A Antibody
Code | Size | Price |
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PSI-60-363-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1, UBASH3A, STS2
Application Note:
For WB starting dilution is: 1:1000
Background:
UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Background References:
- Hinks, A., et al. Ann. Rheum. Dis. (2010) In press :
- Stahl, E.A., et al. Nat. Genet. 42(6):508-514(2010)
- Jin, Y., et al. N. Engl. J. Med. 362(18):1686-1697(2010)
- Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This UBASH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human UBASH3A.
NCBI Gene ID #:
53347
NCBI Official Name:
Ubiquitin-associated and SH3 domain-containing protein A
NCBI Official Symbol:
UBASH3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
P57075
Protein GI Number:
10720330
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P57075
User NOte:
Optimal dilutions for each application to be determined by the researcher.