Mouse Nod1 Antibody
Code | Size | Price |
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PSI-60-392-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, Nod1, Card4
Application Note:
For WB starting dilution is: 1:1000
Background:
Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens (By similarity).
Background References:
- Moreno, L., et al. Br. J. Pharmacol. 160(8):1997-2007(2010)
- Iyer, J.K., et al. Infect. Immun. 78(6):2418-2428(2010)
- Watanabe, T., et al. J. Clin. Invest. 120(5):1645-1662(2010)
- Toma, C., et al. J. Immunol. 184(9):5287-5297(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Nod1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-584 amino acids from the Central region of mouse Nod1.
NCBI Gene ID #:
107607
NCBI Official Name:
Nucleotide-binding oligomerization domain-containing protein 1
NCBI Official Symbol:
Nod1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
Q8BHB0
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8BHB0
User NOte:
Optimal dilutions for each application to be determined by the researcher.