RASD1 Antibody

ProSci
Product Code: PSI-56-854
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-854-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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RASD1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in mouse liver tissue lysates (35ug/lane).
RASD1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Dexamethasone-induced Ras-related protein 1, Activator of G-protein signaling 1, RASD1, AGS1, DEXRAS1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.
Background References:
  • Nojima, M., et al. Clin. Cancer Res. 15(13):4356-4364(2009)
  • Lau, K.F., et al. J. Biol. Chem. 283(50):34728-34737(2008)
  • Attarzadeh-Yazdi, G., et al. Neurochem. Res. 33(4):609-613(2008)
  • Cheng, H.Y., et al. J. Neurosci. 26(50):12984-12995(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the C-terminal region of human RASD1.
NCBI Gene ID #:
51655
NCBI Official Name:
Dexamethasone-induced Ras-related protein 1
NCBI Official Symbol:
RASD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q9Y272
Protein GI Number:
38258272
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
Q9Y272
User NOte:
Optimal dilutions for each application to be determined by the researcher.