TRIM69 Antibody
Code | Size | Price |
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PSI-56-233-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
E3 ubiquitin-protein ligase TRIM69, 632-, RFP-like domain-containing protein trimless, RING finger protein 36, Tripartite motif-containing protein 69, TRIM69, RNF36
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the RING-B-box-coiled-coil
(RBCC) family and encodes a protein with an N-terminal RING finger
motif, a PRY domain and a C-terminal SPRY domain. The mouse
ortholog of this gene is specifically expressed in germ cells at
the round spermatid stages during spermatogenesis and, when
overexpressed, induces apoptosis. Alternatively spliced transcript
variants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity).
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Shyu, H.W., et al. Exp. Cell Res. 287(2):301-313(2003)
- Shyu, H.W., et al. Mech. Dev. 108 (1-2), 213-216 (2001) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This TRIM69 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human TRIM69.
NCBI Gene ID #:
140691
NCBI Official Name:
E3 ubiquitin-protein ligase TRIM69
NCBI Official Symbol:
TRIM69
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q86WT6
Protein GI Number:
229462760
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
Q86WT6
User NOte:
Optimal dilutions for each application to be determined by the researcher.