Mouse Dcc Antibody

ProSci
Product Code: PSI-60-397
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-397-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstratedetected the Dcc protein (arrow).

Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstratedetected the Dcc protein (arrow).

Further Information

Additional Names:
Netrin receptor DCC, Tumor suppressor protein DCC, Dcc
Application Note:
For WB starting dilution is: 1:1000
Background:
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This Mouse Dcc antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1391-1417 amino acids from the C-terminal region of mouse Dcc.
NCBI Gene ID #:
13176
NCBI Official Name:
Netrin receptor DCC
NCBI Official Symbol:
Dcc
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
158 kDa
Protein Accession #:
P70211
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
P70211
User NOte:
Optimal dilutions for each application to be determined by the researcher.