Mouse Map3k14 Antibody
Code | Size | Price |
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PSI-57-519-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, Map3k14, Nik
Application Note:
For WB starting dilution is: 1:1000
Background:
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Background References:
- Bhattacharyya, S., et al. Exp. Cell Res. 316(19):3317-3327(2010)
- Maeda, Y., et al. Int. Immunol. 22(6):515-525(2010)
- Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
- Takeshima, T., et al. Cancer Res. 70(7):2697-2706(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 amino acids from the C-terminal region of mouse Map3k14.
NCBI Gene ID #:
53859
NCBI Official Name:
Mitogen-activated protein kinase kinase kinase 14
NCBI Official Symbol:
Map3k14
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
103 kDa
Protein Accession #:
Q9WUL6
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9WUL6
User NOte:
Optimal dilutions for each application to be determined by the researcher.