ACTR1A Antibody
| Code | Size | Price |
|---|
| PSI-58-272-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog, ACTR1A, CTRN1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a 42.6 kD subunit of dynactin, a
macromolecular complex consisting of 10-11 subunits ranging in size
from 22 to 150 kD. Dynactin binds to both microtubules and
cytoplasmic dynein. It is involved in a diverse array of cellular
functions, including ER-to-Golgi transport, the centripetal
movement of lysosomes and endosomes, spindle formation, chromosome
movement, nuclear positioning, and axonogenesis. This subunit is
present in 8-13 copies per dynactin molecule, and is the most
abundant molecule in the dynactin complex. It is an actin-related
protein, and is approximately 60% identical at the amino acid level
to conventional actin.
Background References:
- Sugarbaker, D.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(9):3521-3526(2008)
- Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
- Casenghi, M., et al. Dev. Cell 5(1):113-125(2003)
- Carew, J.A., et al. J. Thromb. Haemost. 1(6):1220-1227(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A.
NCBI Gene ID #:
10121
NCBI Official Name:
Alpha-centractin
NCBI Official Symbol:
ACTR1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P61163
Protein GI Number:
47117651
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P61163
User NOte:
Optimal dilutions for each application to be determined by the researcher.