Mouse TLR8 Antibody
| Code | Size | Price |
|---|
| PSI-58-166-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Toll-like receptor 8, CD288, Tlr8
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Background References:
- Kaishoand Akira S, Curr. Mol. Med. 2003. 3: 373.
- Medzhitovand Janeway C, Cell. 1997. 91: 295.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8.
NCBI Gene ID #:
170744
NCBI Official Name:
Toll-like receptor 8
NCBI Official Symbol:
Tlr8
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
119 kDa
Protein Accession #:
P58682
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,
Swissprot #:
P58682
User NOte:
Optimal dilutions for each application to be determined by the researcher.