Mouse Irak3 Antibody
| Code | Size | Price |
|---|
| PSI-57-600-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, Irak3 {ECO:0000312|MGI:MGI:1921164}
Application Note:
For WB starting dilution is: 1:1000
Background:
Irak3 inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Background References:
- Turnis, M.E., et al. J. Immunol. 185(7):4223-4232(2010)
- Hubbard, L.L., et al. J. Immunol. 184(11):6299-6308(2010)
- Seki, M., et al. J. Immunol. 184(3):1410-1418(2010)
- Lyn-Kew, K., et al. PLoS ONE(6), E11145 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Irak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-544 amino acids from the C-terminal region of mouse Irak3.
NCBI Gene ID #:
73914
NCBI Official Name:
Interleukin-1 receptor-associated kinase 3
NCBI Official Symbol:
Irak3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q8K4B2
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8K4B2
User NOte:
Optimal dilutions for each application to be determined by the researcher.