NSMAF Antibody
| Code | Size | Price |
|---|
| PSI-57-140-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation, NSMAF, FAN
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a WD-repeat protein that binds the
cytoplasmic sphingomyelinase activation domain of the 55kD tumor
necrosis factor receptor. This protein is required for TNF-mediated
activation of neutral sphingomyelinase and may play a role in
regulating TNF-induced cellular responses such as inflammation.
Alternative splicing results in multiple transcript variants.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Clarke, C.J., et al. Mol. Pharmacol. 74(4):1022-1032(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NSMAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human NSMAF.
NCBI Gene ID #:
8439
NCBI Official Name:
Protein FAN
NCBI Official Symbol:
NSMAF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
Protein Accession #:
Q92636
Protein GI Number:
209572614
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q92636
User NOte:
Optimal dilutions for each application to be determined by the researcher.