Mouse TRPV3 Antibody

ProSci
Product Code: PSI-57-599
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-599-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western Blot at 1:1000 dilution + mouse heart lysate Lysates/proteins at 20 ug per lane.
2 / 2
Formalin-fixed and paraffin-embedded human testis tissue reacted with TRPV3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western Blot at 1:1000 dilution + mouse heart lysate Lysates/proteins at 20 ug per lane.
Formalin-fixed and paraffin-embedded human testis tissue reacted with TRPV3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Transient receptor potential cation channel subfamily V member 3, TrpV3, Trpv3
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
TRPV3 belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.
Background References:
  • Frederick,J., Biochem. Biophys. Res. Commun. 358 (4), 1058-1064 (2007)
  • Asakawa,M., J. Invest. Dermatol. 126 (12), 2664-2672 (2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse TRPV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of mouse TRPV3.
NCBI Gene ID #:
246788
NCBI Official Name:
Transient receptor potential cation channel subfamily V member 3
NCBI Official Symbol:
Trpv3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
91 kDa
Protein Accession #:
Q8K424
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Research Area:
Neuroscience
Swissprot #:
Q8K424
User NOte:
Optimal dilutions for each application to be determined by the researcher.