Junctophilin 3 Antibody
| Code | Size | Price |
|---|
| PSI-61-445-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
Background References:
- Kakizawa,S., EMBO J. 26 (7), 1924-1933 (2007)
- Moriguchi,S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)
- Nishi,M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)
- Nishi,M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Human
Immunogen:
This Junctophilin 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human Junctophilin 3.
NCBI Gene ID #:
57340
NCBI Official Name:
Junctophilin-3
NCBI Official Symbol:
Jph3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
Q9ET77
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Research Area:
Neuroscience
Swissprot #:
Q9ET77
User NOte:
Optimal dilutions for each application to be determined by the researcher.