OTOA Antibody
| Code | Size | Price |
|---|
| PSI-55-669-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Otoancorin, OTOA
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is specifically expressed
in the inner ear, and is located at the interface between the
apical surface of the inner ear sensory epithelia and their
overlying acellular gels. It is prposed that this protein is
involved in the attachment of the inner ear acellular gels to the
apical surface of the underlying nonsensory cells. Mutations in
this gene are associated with autosomal recessive deafness type 22
(DFNB22). Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Shahin, H., et al. Eur. J. Hum. Genet. 18(4):407-413(2010)
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Hofmann, O., et al. Proc. Natl. Acad. Sci. U.S.A. 105(51):20422-20427(2008)
- Zwaenepoel, I., et al. Proc. Natl. Acad. Sci. U.S.A. 99(9):6240-6245(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This OTOA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human OTOA.
NCBI Gene ID #:
146183
NCBI Official Name:
Otoancorin
NCBI Official Symbol:
OTOA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
129 kDa
Protein Accession #:
Q7RTW8
Protein GI Number:
56404568
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q7RTW8
User NOte:
Optimal dilutions for each application to be determined by the researcher.