GRIN2C Antibody

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ProSci
Product Code: PSI-60-708
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-708-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

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Further Information

Additional Names:
Glutamate receptor ionotropic, NMDA 2C, GluN2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C, GRIN2C, NMDAR2C
Application Note:
For WB starting dilution is: 1:1000
Background:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq].
Background References:
  • Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
  • Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
  • Shi, J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (7), 1270-1277 (2008) :
  • Self, R.L., et al. Brain Res. 995(1):39-45(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.
NCBI Gene ID #:
2905
NCBI Official Name:
Glutamate receptor ionotropic, NMDA 2C
NCBI Official Symbol:
GRIN2C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
134 kDa
Protein Accession #:
Q14957
Protein GI Number:
313104210
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,
Swissprot #:
Q14957
User NOte:
Optimal dilutions for each application to be determined by the researcher.