GRIN2A Antibody
| Code | Size | Price |
|---|
| PSI-55-788-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
N-methyl-D-aspartate (NMDA) receptors are a class of
ionotropic glutamate-gated ion channels. These receptors have been
shown to be involved in long-term potentiation, an
activity-dependent increase in the efficiency of synaptic
transmission thought to underlie certain kinds of memory and
learning. NMDA receptor channels are heteromers composed of the key
receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2
subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and
NMDAR2D (GRIN2D). Alternatively spliced transcript variants
encoding different isoforms have been found for this gene.
Background References:
- Endele, S., et al. Nat. Genet. 42(11):1021-1026(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Saus, E., et al.Psychiatr Res 44(14):971-978(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1057-1084 amino acids from the Central region of human GRIN2A.
NCBI Gene ID #:
2903
NCBI Official Name:
Glutamate receptor ionotropic, NMDA 2A
NCBI Official Symbol:
GRIN2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
165 kDa
Protein Accession #:
Q12879
Protein GI Number:
14285603
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,
Swissprot #:
Q12879
User NOte:
Optimal dilutions for each application to be determined by the researcher.