PPP2R5A Antibody

ProSci
Product Code: PSI-58-139
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-139-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse liver tissue lysates (35ug/lane).

Western blot analysis in mouse liver tissue lysates (35ug/lane).

Further Information

Additional Names:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha, PPP2R5A
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily.
Background References:
  • Flegg, C.P., et al. J. Biol. Chem. 285(24):18144-18154(2010)
  • Freeman, A.K., et al. Cell Cycle 9(4):736-747(2010)
  • Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386(4):582-587(2009)
  • Li, H., et al. Mol. Cell. Biol. 29(3):919-928(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPP2R5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the C-terminal region of human PPP2R5A.
NCBI Gene ID #:
5525
NCBI Official Name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
NCBI Official Symbol:
PPP2R5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q15172
Protein GI Number:
7387496
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q15172
User NOte:
Optimal dilutions for each application to be determined by the researcher.